Gascon是療效不明確的藥物嗎？？那審查醫師是身分未明的醫師!?
發表於 : 週四 4月 01, 2010 5:41 pm
至少公布醫師證書字號吧~
我敢說我熟讀 Clinical and Basic Pharmacology,同時也知道 Clinical Therapeutics.
Gascon 是Semithicon ,是 siloxane polymers and silicon dioxide ( Si o2)的混合物.
Simethicone 常用做oral antiflatulent agent,但FDA並未核准這用途.
1.Although simethicone is widely used and a relatively safe product, its efficacy for the treatment of gas is controversial.(Anonymous. Simethicone for gastrointestinal gas. Med Lett Drugs Ther 1996;38:57-58.)
2.Simethicone has not been shown beneficial in infant colic, and although safe, was no more effective than placebo.(Metcalf TJ, Irons TG, Sher LD, et al. Simethicone in the treatment of infant colic: a randomized, placebo-controlled, multicenter trial. Pediatrics 1994;94:29-34.)
3.用在內視鏡, Radiology做為antifoaming agent 是有用的.
Simethicone-coated cellulose suspension is an oral agent used to enhance upper GI visibility in ultrasound images by reducing gas shadowing, but is not indicated for routine use as an antiflatulent.
答案是可用在flactulent,但療效是如何?