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更新日期:2010/07/31 02:58 潘勛／綜合報導
中國時報【潘勛／綜合報導】
許多女性為了避免骨質疏鬆而每天服用鈣片，然而英國、紐西蘭最新醫學研究指出，五十歲以上婦女天天服用鈣質補充劑，罹患心臟病的機率將增加三成；專家建議，為防止骨質疏鬆，鈣質最好由飲食中攝取。
英國亞伯丁大學及紐西蘭奧克蘭大學專家綜合分析十一項臨床試驗後發現，每一千人服用鈣補充劑，歷時五年，能防止的骨折案例為廿六件，但導致十四件心臟病例、十件中風病例以及十三人死亡。
專家表示，由高鈣飲食攝取鈣質者，罹患心臟病的機率並不會增加，所以顯然是鈣質補充劑增加了血液中鈣的濃度，造成血管硬化，反而對心血管造成負面影響。研究成果刊於《英國醫學雜誌》（British Medical Journal）線上版。
學者們指出，鈣質補充劑對骨質密度、預防骨折只有些許好處，卻會增加心臟病發的機率，也因此，就預防骨質疏鬆而言，實有必要重估鈣質補充劑的功效。
吃鈣片強骨 心臟病機率多3成
版主: 版主021
Re: 吃鈣片強骨 心臟病機率多3成
原文出處：
http://www.bmj.com/cgi/content/full/341/jul29_1/c3691
Results
15 trials were eligible for inclusion, five with patient level data (8151 participants, median follow-up 3.6 years, interquartile range 2.7-4.3 years) and 11 with trial level data (11 921 participants, mean duration 4.0 years).
In the five studies contributing patient level data, 143 people allocated to calcium had a myocardial infarction compared with 111 allocated to placebo (hazard ratio 1.31, 95% confidence interval 1.02 to 1.67, P=0.035).
Non-significant increases occurred in the incidence of stroke (1.20, 0.96 to 1.50, P=0.11), the composite end point of myocardial infarction, stroke, or sudden death (1.18, 1.00 to 1.39, P=0.057), and death (1.09, 0.96 to 1.23, P=0.18).
The meta-analysis of trial level data showed similar results: 296 people had a myocardial infarction (166 allocated to calcium, 130 to placebo), with an increased incidence of myocardial infarction in those allocated to calcium (pooled relative risk 1.27, 95% confidence interval 1.01 to 1.59, P=0.038).
http://www.bmj.com/cgi/content/full/341/jul29_1/c3691
Results
15 trials were eligible for inclusion, five with patient level data (8151 participants, median follow-up 3.6 years, interquartile range 2.7-4.3 years) and 11 with trial level data (11 921 participants, mean duration 4.0 years).
In the five studies contributing patient level data, 143 people allocated to calcium had a myocardial infarction compared with 111 allocated to placebo (hazard ratio 1.31, 95% confidence interval 1.02 to 1.67, P=0.035).
Non-significant increases occurred in the incidence of stroke (1.20, 0.96 to 1.50, P=0.11), the composite end point of myocardial infarction, stroke, or sudden death (1.18, 1.00 to 1.39, P=0.057), and death (1.09, 0.96 to 1.23, P=0.18).
The meta-analysis of trial level data showed similar results: 296 people had a myocardial infarction (166 allocated to calcium, 130 to placebo), with an increased incidence of myocardial infarction in those allocated to calcium (pooled relative risk 1.27, 95% confidence interval 1.01 to 1.59, P=0.038).
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joelin
- 指導教授
- 文章: 9364
- 註冊時間: 週六 4月 14, 2007 11:12 pm
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poki
- V4
- 文章: 4516
- 註冊時間: 週一 11月 13, 2006 5:24 am
Re: 吃鈣片強骨 心臟病機率多3成
鈣片吃了, 骨頭硬, 血管也跟著硬了hjh 寫:為什麼鈣片就會增加risk
飲食不會?
(咦)
高鈣飲食, 其實鈣不高, 血管不硬的, 骨頭也不硬安等同無效 (咦)
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Thanatos
- 指導教授
- 文章: 9134
- 註冊時間: 週四 5月 13, 2010 9:23 am
- 來自: 烏賊帝國
Re: 吃鈣片強骨 心臟病機率多3成
這種nutrition的study
常常和SES, lifestyle和healthy behavior都有關係
一堆confounding
我大概就把它當成association study的推論
參考參考
現在醫療新聞越奇怪駭人的越會被點閱不是嗎
沒有客觀reading paper的訓練
民眾還是只能被頭條標題簽著走
跟仇醫新聞一樣阿
常常和SES, lifestyle和healthy behavior都有關係
一堆confounding
我大概就把它當成association study的推論
參考參考
現在醫療新聞越奇怪駭人的越會被點閱不是嗎
沒有客觀reading paper的訓練
民眾還是只能被頭條標題簽著走
跟仇醫新聞一樣阿
人生哪有辦得完
知是夢幻哪來坎
理上辦事存善念
忽然夢了記得返
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yang0945
- V1
- 文章: 1068
- 註冊時間: 週二 7月 28, 2009 8:15 pm
Re: 吃鈣片強骨 心臟病機率多3成
+1Thanatos 寫:這種nutrition的study
常常和SES, lifestyle和healthy behavior都有關係
一堆confounding
我大概就把它當成association study的推論
參考參考
現在醫療新聞越奇怪駭人的越會被點閱不是嗎
沒有客觀reading paper的訓練
民眾還是只能被頭條標題簽著走
跟仇醫新聞一樣阿