糖尿病用藥臭如髒襪子 美醫師:難怪病患噁心
更新日期:2010/02/16 10:09
(路透華盛頓15日電)美國多位醫師今天報告,糖尿病常用藥metformin真臭,這也許是許多病患停止服藥的原因。
他們表示,對某些人來說,這種藥物聞起來像魚或髒襪子,這可說明此藥為什麼有讓人噁心的副作用。
他們致函「內科醫學年鑑」(Annals of Internal Medicine)表示,解決這個問題的方法是把metformin做成糖衣式藥丸,就不會有臭味,也不會在胃內釋放異味,導致打嗝發出臭氣。
喬治亞醫學院(Medical College of Georgia)的白耶悌(Allen Pelletier)與同僚在信中指出:「我們不解這個現象之前怎麼沒被披露過。」他們說:「病患可能通報metformin讓他們噁心,可是沒有進一步詳述或區別這是內臟對藥物氣味所產生的反應。」中央社(翻譯)
(勾拳一記)
是真的嗎
自己都沒吃過
糖尿病用藥臭如髒襪子 美醫師:難怪病患噁心
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Re: 糖尿病用藥臭如髒襪子 美醫師:難怪病患噁心
Metformin's Fishy Smell May Account for Drug Discontinuation
Patients taking generic versions of the diabetes drug metformin may report a "fishy" smell, researchers describe in the Annals of Internal Medicine.
The authors describe two case reports in which patients stopped taking generic metformin after being nauseated by the drug's fish-like smell. Pharmacists have also noted the peculiar odor, "like old locker-room sweat socks," the authors write.
They conclude: "When patients stop taking metformin, physicians should consider inquiring more closely about revulsion to the odor of the medication. Trial of a film-coated, extended-release formulation may be a reasonable approach in such cases."
Patients taking generic versions of the diabetes drug metformin may report a "fishy" smell, researchers describe in the Annals of Internal Medicine.
The authors describe two case reports in which patients stopped taking generic metformin after being nauseated by the drug's fish-like smell. Pharmacists have also noted the peculiar odor, "like old locker-room sweat socks," the authors write.
They conclude: "When patients stop taking metformin, physicians should consider inquiring more closely about revulsion to the odor of the medication. Trial of a film-coated, extended-release formulation may be a reasonable approach in such cases."
'We are all just prisoners here of our own device'
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